Rapid prototyped patient specific guiding implants in critical mandibular reconstruction

Rapid prototyped implants Adult Male SURGERY Surgery, anesthesiology, intensive care, radiology INNOVATIONS Surgical Flaps 03 medical and health sciences 0302 clinical medicine FRACTURES DESIGN Mandibular reconstruction Bone-Implant Interface Humans Prospective Studies Aged REPAIR Tissue Scaffolds Microvascular reconstruction Prostheses and Implants Middle Aged ORBITAL WALL DEFECTS Mandibular Neoplasms Dentistry Computer-Aided Design FLAPS Female Mandibular Reconstruction
DOI: 10.1016/j.jcms.2016.10.021 Publication Date: 2016-11-05T06:31:49Z
ABSTRACT
Large tumours of the mandible need immediate reconstruction to provide continuity of the mandible, satisfactory function of the jaw, as well as an acceptable aesthetic outcome. In this prospective study we described the immediate reconstruction of the mandible using computer aided design and 15 rapid prototyped patient specific implants (PSI) in 14 patients suffering from benign or malignant tumours demanding continuity resection of the mandible. The scaffold PSI was filled with β-tricalcium phosphate granules and autologous bone. Microvascular reconstruction was additionally needed in 12/15 cases. The clinical follow up was on average 33 months and the radiological follow up was on average 21 months. In nine cases the healing was uneventful. One patient lost the microvascular flap during the first postoperative week and one patient needed a revision due to perforation of the mucosa at the site of the PSI. Four patients had a major complication due to perforation of the mucosa leading to infection, which resulted in the total or partial removal of the PSI. The PSI seems to be a promising solution for treatment of patients demanding large reconstruction after mandible resection. The benefits are decreased rate of donor site complications and more accurate and prompt surgical procedure.
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