A case of generalized morphea profunda following SARS-CoV-2 infection

• DOI: 10.1016/j.jdcr.2022.02.033
• Publication Date: 2022-03-12T07:35:45Z
• Authors: Michael R. Stephens; Duncan F. Moore; Jonathan Dau; Soma Jobbagy; Victor A. Neel; Marcy B. Bolster; Flavia Fedeles
• Keywords: Morphea; Pathogenesis; Immune Dysregulation

Morphea is an immune-mediated fibrosing skin disorder of the dermis and subcutaneous fat with unclear pathogenesis triggers. Combinations genetic environmental factors leading to immune dysregulation are likely involved. Here, we describe a case generalized morphea profunda occurring after SARS-CoV-2 infection, discuss possible causality pathogenesis.