Shuangshen ningxin formula attenuates cardiac microvascular ischemia/reperfusion injury through improving mitochondrial function

• DOI: 10.1016/j.jep.2023.117690
• Publication Date: 2024-01-07T22:35:05Z
• Authors: ZiXin Liu; Xiao Han; Yue You; GaoJie Xin; LingMei Li; JiaMing Gao; HongXu Meng; Ce Cao; JianXun Liu; YeHao Zhang; Lei Li; JianHua Fu
• Keywords: Terminal deoxynucleotidyl transferase

Shuangshen Ningxin Formula (SSNX) is a traditional Chinese medicine formula used to treat myocardial ischemia-reperfusion injury (MIRI). A randomized controlled trial previously showed that SSNX reduced cardiovascular events, and experiments have also verified attenuated (I/R) injury. However, the mechanism of in treatment microvascular I/R still unclear.