A Genome-Wide Association Study for Morphometric Traits in Quarter Horse

• DOI: 10.1016/j.jevs.2014.05.011
• Publication Date: 2014-05-24T16:17:50Z
• Authors: Camila Tangari Meira; Michel Marques Farah; Marina R.S. Fortes; Stephen S. Moore; Guilherme L. Pereira; Josineudson Augus...; Marcílio Dias S. ...; Rogério Abdallah ...
• Keywords: Genome-wide Association Study; Rump; Genetic Association; Candidate gene

A genome-wide association study for morphometric traits was conducted in 184 Quarter Horses, 120 from a racing population, and 64 cutting which were genotyped using the Illumina EquineSNP50 chip. Association analysis performed with 42,058 single-nucleotide polymorphisms (SNPs) (after quality control) Qxpak5 software. The following measured: weight (W), rump length (RL), body (BL). These are important best performance race events. For weight, three SNPs associated (P < .0001) found on chromosomes (Equus caballus autosomes [ECA]) 2 3. length, eight ECA 2, 3, 6, 7, 9, 21, 26. On 3 8, two length. So, total of 13 chromosomal regions identified Q values 0.53 (SNPs W), 0.40 RL), 0.99 BL). Positional functional candidate genes emerging this WWOX AAVPR1A. Further studies required to confirm these associations other populations.