Effect of the emulsion of Sacha Inchi (Plukenetia huayabambana) oil on oxidative stress and inflammation in rats induced to obesity

• DOI: 10.1016/j.jff.2019.103631
• Publication Date: 2019-11-03T11:25:28Z
• Authors: Johnny P. Ambulay; Percy A. Rojas; Olga S. Timoteo; Teresa V. Barreto; Ana Colarossi
• Keywords: Oil Red O; Lipid Profile

Sacha Inchi (Plukenetia huayllabambana), an oleoleguminosae with a high content ω-3, could help normalize alterations of obesity. We evaluated the effect emulsion (SI) oil on lipid profile, oxidative stress and inflammation in serum liver tissue obesity-induced rats. Five groups induced to obesity by high-fat diet were analyzed. One group without treatment, two SI (OSI1:0.25 ω-3/day, OSI2:0.5 ω-3/day), one atorvastatin plus oil. The treated lowered values total cholesterol, triglycerides, LDLc, increased HDLc. protein oxidation marker, IL-6 leptin decreased serum, as well TNF-α hepatic. In contrast, adiponectin, antioxidant capacity, catalase activity OSI2 group. Therefore, normalizes profile decreases model.