Ginseng soluble dietary fiber can regulate the intestinal flora structure, promote colon health, affect appetite and glucolipid metabolism in rats

• DOI: 10.1016/j.jff.2021.104534
• Publication Date: 2021-05-27T23:12:20Z
• Authors: Mei Hua; Meiling Fan; Zhiman Li; Jiyue Sha; Shanshan Li; Yinshi Sun
• Keywords: Ruminococcus

In this study, the effects of ginseng water-soluble dietary fiber (ginseng-SDF) on metabolism, appetite and colon health in rats were investigated. The results showed that ginseng-SDF could improve glucolipid especially triglyceride levels. Ginseng-SDF also increased satiety delayed gastric emptying by regulating hormone levels as ghrelin, glucagon-like peptide-1, peptide YY, cholecystokinin. addition, improved intestinal structures enhanced fecal short-chain fatty acids concentrations (especially acetic acid butyric acid). More importantly, affected abundance Firmicutes Bacteroides, significantly promoted proliferation probiotics cellulolytic bacteria such Lactobacillus, Bifidobacterium Ruminococcus_bromii. Among them, pseudolongum, Lactobacillus helveticus R. bromii correlated with blood glucose lipid These suggested alter flora structure, promote health, ultimately have a positive impact metabolism energy homeostasis.