Surgical site infections after simultaneous pancreas kidney and pancreas transplantation in the Swiss Transplant Cohort Study

• DOI: 10.1016/j.jhin.2022.07.009
• Publication Date: 2022-07-14T06:32:43Z
• Authors: P.W. Schreiber; M. Laager; K. Boggian; D. Neofytos; C. van Delden; A. Egli; M. Dickenmann; C. Hirzel; O. Manuel; M. Koller; S. Rossi; B. Schmied; L. Gürke; M. Matter; T. Berney; O. de Rougemont; S.P. Kuster; S. Stampf; N.J. Mueller; P. Amico; J-D. Aubert; V. Banz; S. Beckmann; G. Beldi; C. Berger; E. Berishvili; A. Berzigotti; I. Binet; P-Y. Bochud; S. Branca; H. Bucher; E. Catana; A. Cairoli; Y. Chalandon; S. De Geest; O. De Rougemont; S. De Seigneux; M. Dickenmann; J.L. Dreifuss; M. Duchosal; T. Fehr; S. Ferrari-Lacraz; C. Garzoni; D. Golshayan; N. Goossens; F.H.J. Halter; D. Heim; C. Hess; S. Hillinger; H.H. Hirsch; P. Hirt; G. Hofbauer; U. Huynh-Do; F. Immer; M. Koller; M. Laager; B. Laesser; F. Lamoth; R. Lehmann; A. Leichtle; O. Manuel; H.P. Marti; M. Martinelli; V. McLin; K. Mellac; A. Merçay; K. Mettler; A. Müller; N.J. Mueller; U. Müller-Arndt; B. Müllhaupt; M. Nägeli; G. Oldani; M. Pascual; J. Passweg; R. Pazeller; K. Posfay-Barbe; J. Rick; A. Rosselet; S. Rossi; S. Rothlin; F. Ruschitzka; T. Schachtner; U. Schanz; S. Schaub; A. Scherrer; A. Schnyder; M. Schuurmans; S. Schwab; T. Sengstag; F. Simonetta; S. Stampf; J. Steiger; G. Stirnimann; U. Stürzinger; C. Van Delden; J-P. Venetz; J. Villard; J. Vionnet; M. Wick; M. Wilhelm; P. Yerly
• Keywords: Interquartile range; Immunosuppression; Pancreas transplantation

Among hospital-acquired infections, surgical site infections (SSIs) are frequent. SSI in the early post-transplant course poses a relevant threat to transplant recipients.To determine incidence, risk factors for and its association with outcomes pancreas (P-Tx) recipients.Adult simultaneous kidney-pancreas transplantation (SPK-T) P-Tx recipients follow-up of at least 90 days were identified Swiss Transplant Cohort Study (STCS) dataset. Except categorization SSIs according Centers Disease Control Prevention (CDC) criteria, all other data prospectively collected. Risk investigated logistic regression. A Weibull accelerated failure-time model was applied address impact on length stay, correcting transplant-related complications delayed graft function.Of 130 recipients, 108 SPK-Tx 22 P-Tx, 18 (14%) individuals developed within first after transplantation. Deep incisional (seven, 38.9%) organ/space (eight, 44.4%) predominated. In majority (11, 61.1%; two identification fungal pathogens) bacteria detected Enterococcus spp. being most The median duration hospitalization significantly longer (median: 26 days; interquartile range (IQR): 19-44) than patients without 17 IQR: 12-25; P = 0.002). multivariate analysis, associated increased stay prolonged by 36% (95% confidence interval: 4-79).SSI occurred frequency 14%. pathogens, independently