Effects of proteins on magnesium degradation - static vs. dynamic conditions

• DOI: 10.1016/j.jma.2021.07.021
• Publication Date: 2021-09-04T11:38:40Z
• Authors: Ruiqing Hou; Frank Feyerabend; Heike Helmholz; Vasil M. Garamus; Regine Willumeit-...
• Keywords: Degradation

The interaction between organic molecules and biomaterial surfaces determines the fate of biomaterials during their service life, which is also research hotspots in field biomaterials. To understand mechanism protein with magnesium (Mg) degradation, alloying elements, immersion time, concentration surface conditions have been previously considered for effect proteins on Mg degradation. However, fluid flow, as one critical factors, drew little attention this case. In present study, bovine serum albumin (BSA) fetal (FBS) degradation was compared under static dynamic conditions. results revealed that both BSA FBS slightly decreased rate Hanks' balanced salt solution (HBSS) due to adsorption formation a Ca/P-rich top layer surface, whereas flow condition significantly accelerated presence or FBS. reasons seemed stem from weakened case dynamically enhanced ions/products solutions, largely weaken combination inner corrosion product layer. These highlight importance testing characterization vitro synergistic different parameters