Effects of metal ion implantation (Fe, Ti, Zn and Zr) on mechanical properties, corrosion resistance and biocompatibility of WE43 Mg alloy

• DOI: 10.1016/j.jma.2024.05.005
• Publication Date: 2024-05-22T12:32:32Z
• Authors: Lianhui Li; Zhiqiang Zhang; Dechuang Zhang; Fugang Qi; Yilong Dai; Wenwen Wei; Xiaoping Ouyang
• Keywords: Biocompatibility

To improve the corrosion resistance of biodegradable Mg alloys, WE43 alloys were implanted with Fe, Ti, Zn and Zr ions at same implantation dose. The surface morphology, valence state elements, nano-hardness (NH), elastic modulus (EM), degradation rate in vitro cell experiments modified systematically studied. A layer composed Mg, MgO, elements their oxides was formed on alloys. Since high-speed metal caused severe lattice damage, hardness substrate considerable increased. Electrochemical tests demonstrated a substantial enhancement via Ti ions, resulting reduction current density to 88.1 ± 9.9 15.6 11.4 µA cm−2, respectively, compared Fe ions. Biocompatibility showed that enhanced anticoagulant hemolytic alloy. All surface-modified samples negligible cytotoxicity (0–1) 12.5% extract concentration. Moreover, significantly promoted proliferation human umbilical vein endothelial cells (HUVEC) unmodified results demonstrate ion is best choice for alloy modification achieve outstanding biocompatibility.