Magnetic resonance microscopy of biofilm structure and impact on transport in a capillary bioreactor

0301 basic medicine Microscopy Magnetic Resonance Spectroscopy Biological Transport, Active Water Image Enhancement Magnetic Resonance Imaging 03 medical and health sciences Bioreactors Biofilms Staphylococcus epidermidis Rheology Capillary Action
DOI: 10.1016/j.jmr.2004.01.009 Publication Date: 2004-02-07T10:16:00Z
ABSTRACT
Microorganisms that colonize surfaces, biofilms, are of significant importance due to their role in medical infections, subsurface contaminant remediation, and industrial processing. Spatially resolved data on the distribution of biomass within a capillary bioreactor, the heterogeneity of the biofilm itself and the impact on transport dynamics for a Staphylococcus epidermidis biofilm in the natural growth state are presented. The data demonstrate the ability of magnetic resonance microscopy to study spatially resolved processes in bacterial biofilms, thus providing a basis for future studies of spatially resolved metabolism and in vivo clinical detection.
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