Bioengineering, characterization, and biological activities of C@CuO@Cu nanocomposite based-mediated the Vicia faba seeds aqueous extract

• DOI: 10.1016/j.jmrt.2021.07.076
• Publication Date: 2021-07-27T09:00:56Z
• Authors: Mostafa F. Al-Hak...; Sedky H.A. Hassan; Mohammed S. Saddik; Mohamed A. El-Mok...; Samah A. Al-Shelkamy
• Keywords: Zeta potential; Selected area diffraction

Vicia faba seeds are a rich source of polyphenolic, and flavonoid compounds that have high antioxidant activity. The aqueous extract V. has been used for the biosynthesis nanocomposite (NC) consisting three different types nanoparticles deposited onto each other as [email protected]2[email protected]. Physicochemical, optical, electrical, morphological properties as-biofabricated protected] NC were characterized using analytical techniques X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FT-IR), Ultraviolet–visible (UV–Vis), Photoluminescence (PL), Transmission Electron Microscopy (TEM), Scanning (SEM), Energy Dispersive X-Ray (EDX), Raman, Zeta-potential, water/moisture content). Results confirmed mediated fabrication at pure crystalline nature. nano-formulation had face center cubic crystallographic system nano-scale range Debye–Scherrer's equation (13.8 nm) in XRD analysis (20.9 ± 6.2 TEM analysis. crystallinity index (1.6) with large surface area polycrystalline nature being investigated. In addition, biological activity synthesized was analyzed. showed anti-inflammatory compared diclofenac potassium IC50 = 213.3 μg/mL. Moreover, potent antibacterial activity, particularly against Gram-negative bacteria. Cytotoxicity MCF7, HCT116, HepG2 cell lines efficient cytotoxic impact 84.8, 116.1, 120.5 μg/mL, respectively. So, may provide promising platform effective treatment cancer.