Effects of total and regional fat loss on plasma CRP and IL-6 in overweight and obese, older adults with knee osteoarthritis

• DOI: 10.1016/j.joca.2014.11.005
• Publication Date: 2014-11-17T01:20:02Z
• Authors: K.M. Beavers; D.P. Beavers; J.J. Newman; A.M. Anderson; R.F. Loeser; B.J. Nicklas; M.F. Lyles; G.D. Miller; S.L. Mihalko; S.P. Messier
• Keywords: Male; Weight loss; Total body fat mass; Diet, Reducing; Biomedical Engineering; 03 medical and health sciences; 0302 clinical medicine; Rheumatology; Osteoarthritis; Weight Loss; Humans; Orthopedics and Sports Medicine; Single-Blind Method; Obesity; Exercise; Aged; Inflammation; 2. Zero hunger; Regional fat mass; Interleukin-6; Osteoarthritis, Knee; Overweight; 3. Good health; C-Reactive Protein; Female

To describe associations between total and regional body fat mass loss and reduction of systemic levels of inflammation (C-reactive protein (CRP) and interleukin-6 (IL-6)) in obese, older adults with osteoarthritis, undergoing intentional weight loss.