Measuring biventricular function and left atrial volume in a single five-dimensional whole-heart cardiovascular magnetic resonance scan at 0.55T

• DOI: 10.1016/j.jocmr.2025.101906
• Publication Date: 2025-05-08T21:23:42Z
• Authors: Xavier Sieber; Katherine Binzel; Juliet Varghese; Yingmin Liu; Jerome Yerly; Christopher W. Roy; Panagiotis Antiochos; Milan Prsa; Ruud B. van Heeswijk; Orlando P. Simonetti; Matthias Stuber
• Keywords: Angiology; Ventricular Function; Cardiac magnetic resonance

CMR has not seen widespread adoption beyond large urban academic centers. The reasons for this limited uptake include the cost, time-intensive nature and special expertise of CMR. Self-navigated 5D, x-y-z-cardiac-respiratory, free-funning whole-heart using self-navigation (5D CMR) implemented on a low-field clinical scanner may help bridge gap bi-ventricular function assessment left atrium volume index measurement. Whole-heart 3D radial phyllotaxis bSSFP data were collected in 10 healthy adult subjects. Self-navigation was used to extract respiratory cardiac motion signals generate motion-resolved 5D datasets. right- left-ventricular ejection fraction (RVEF LVEF), atrial (LAVI), contrast ratio, sharpness, perceived image quality, total scan durations ascertained compared those obtained with reference 2D cine images. allowed time-efficient concordant measurements when method. images resulted lower CR (3.3 ± 2.9) than cines (4.7 1.2), similarly quality (1.8 0.8 3.6 0.9 cines). However, LVEF similar no statistically significant differences (Mean: 58 5% 59 cine, p = 0.49) LoA low (-2.81% 3.81%). For RVEF, also good agreement RVEF measured axial views (60 3% 60 4% 0.85) (-2.87% 3.07%). without need ECG, breath-holding, navigators, or complex planning enables highly simplified 0.55T system 7:50min.