Linear and Volumetric Airway Changes After Maxillomandibular Advancement for Obstructive Sleep Apnea

• DOI: 10.1016/j.joms.2014.11.020
• Publication Date: 2014-12-13T02:40:14Z
• Authors: Kevin J. Butterfield; Patricia L.G. Marks; Laurie McLean; Jack Newton
• Keywords: Adult; Male; Anatomy, Cross-Sectional; Cephalometry; Osteotomy, Sagittal Split Ramus; Oropharynx; Endoscopy; Organ Size; Cone-Beam Computed Tomography; Middle Aged; Body Mass Index; 3. Good health; Cohort Studies; 03 medical and health sciences; Imaging, Three-Dimensional; 0302 clinical medicine; Nasopharynx; Humans; Osteotomy, Le Fort; Pharynx; Female; Mandibular Advancement; Follow-Up Studies

Maxillomandibular advancement (MMA) surgery is a well-established treatment of obstructive sleep apnea (OSA). Although many studies have assessed the efficacy of MMA in treating OSA, very few studies have quantified the magnitude of its changes to airway morphology. Therefore, the present study investigated the linear and volumetric morphologic changes that occur in the pharyngeal airway after treatment of OSA using MMA.A retrospective cohort study of patients with OSA treated from May 2010 to February 2014 was performed. Each patient underwent preoperative clinical and fiberoptic nasopharyngoscopic examinations. Pre- and postoperative polysomnograms, lateral cephalograms, and cone-beam computed tomography scans were acquired. The radiographic images were used to determine the linear and volumetric airway measurements. The time and magnitude of skeletal movement were used as the independent variables. The dependent variables included assessment of success or cure, apnea hypopnea index (AHI), cephalometric changes, Epworth score, rapid eye movement sleep, body mass index, and various airway morphologic parameters.A total of 15 patients (13 men and 2 women) participated in the present study. The surgical success and cure rate was 73.33% and 40.00%, respectively. Statistically significant improvements were found in the airway total volume, minimal cross-sectional area, anteroposterior and lateral dimensions, airway index, airway length, posterior airway space morphology, AHI, and Epworth sleepiness score.MMA is a highly successful surgical treatment of OSA that improves airway morphology and sleep quality. MMA results in a shorter and broader airway and associated improvements in the AHI.