Fluorescent carbon dots for highly sensitive bilirubin sensing with excellent selectivity

• DOI: 10.1016/j.jsamd.2023.100599
• Publication Date: 2023-07-01T15:47:48Z
• Authors: Kandasamy Sasikumar; Ramar Rajamanikandan; Heongkyu Ju
• Keywords: Absorbance

We reported the fluorescence sensor of carbon dots (CDs) synthesized for highly sensitive and selective detection bilirubin in human urine. High-resolution transmission electron microscopy (HRTEM) images showed that CDs have a spherical shape with mean particle size 2.6 nm. The fluorescent emission, which peaked at wavelength 511 nm under excitation 435 CDs' emission intensity reduced increasing concentration, was ascribed to strong inner filter effect (IFE). excellent spectral match between absorbance allowed be markedly specific only presence bilirubin, permitting identification even other potentially interfering elements. displayed good linear response concentration wide range 3.5–45.5 μM limit (LOD) 34 nM, being remarkably low level though were facile way without doping. Moreover, this sensing strategy permitted us quantify clinical (real) specimen recovery 95.3–96.8%, indicating great potential candidate cost-effective platform biomedical application.