Decreasing prevalence of vitamin D deficiency in the central region of Saudi Arabia (2008-2017)

• DOI: 10.1016/j.jsbmb.2021.105920
• Publication Date: 2021-05-15T15:24:15Z
• Authors: Nasser M. Al-Daghri; Syed Danish Hussain; Mohammed G.A. Ansari; Malak N.K. Khattak; Naji Aljohani; Yousef Al-Saleh; Mohammed Y. Al-Harbi; Shaun Sabico; Majed S. Alokail
• Keywords: Prediabetes; Demographics

Widespread vitamin D deficiency (serum 25-hydroxyvitamin < 50 nmol/L) in Saudi Arabia (SA) has been documented, yet a time trend is needed to establish where the prevalence headed. This study aims fill this gap.This cross-sectional series (N = 7360) were conducted central region of SA from 2008 2017. Participants all ages taken multiple cohorts that included Biomarker Screening Riyadh (2008-2010; N 1460), Osteoporosis Registry (2014-2017; 1225), Gestational Diabetes Mellitus cohort (2014-2017, 281), Vitamin School Project (2011-2017; 3039) and Prediabetes (2012-2017; 1355) master databases.Vitamin 10-year 73.2 %. Between 2008-2017, decreased 87.1% 64.7% for participants aged 18-40 years (p-trend<0.001), 86.2% 45.7% > 40 (p-trend<0.001). During period, females 80.1% 69.6% whereas males, it 93.2% 49.3% Serum 25(OH)D was observed have an overall increase 2.2 ± 0.1 nmol/l (p 0.001) along with seasonally adjusted annual 1.3 0.2 2017 0.001).The decreasing across demographics suggests successful public health campaigns over time. It will be interesting investigate further whether general improvement status at community level also translated lesser incidences d-related diseases