B-41 | Insights into a Rare Clinical Phenomenon: Selective and Isolated Native Valve Endocarditis Subsequent to Prosthetic Valve Implantation

• DOI: 10.1016/j.jscai.2024.101608
• Publication Date: 2024-05-03T16:59:22Z
• Authors: Sujoy Khasnavis; Majd Al Deen Alhu...; Robert Faillace; Michael Grushko
• Keywords: Phenomenon

Isolated native valve endocarditis (INVE) after prosthetic implantation (PVI) is a rare form of valvular infection. The contributing factors, management, and outcomes for INVE are not as well defined (PVE). A systematic review PubMed, Embase, Web Science was done to identify cases PVI. examined with respect its incidence PVI, age group, gender, comorbidity, infecting pathogen, type, left ventricular ejection fraction, treatment mortality rate. 166 were identified from total 3500 IE mean patients 79 +- 6 years. Males contributed 60% both PVE cases. most common comorbidities in atrial fibrillation 40%, diabetes CKD 35%, COPD 30%, mitral regurgitation 25%, history stroke 10%. In PVE, gram positive bacterial infections present 80% while fungal negative 20%. 99% presented normal fraction. Antibiotic therapy alone used 94% 78% Overall rates 43% 50% 2 year follow up respectively. Of all cases, 96% transcatheter aortic implantation, 0.7% pulmonic surgical homograft 1.9% other implantations. 76% found on valves, 23% right heart 1% valves. makes small but measurable proportion PVI has significant It associated many the patient characteristics, comorbidities, infectious entities seen PVE. Clinically, often attributed only finding portion these Given overlap clinical suspicion should be greater who fit characteristics described this study. This especially true PVIs more frequently reported implants.