Synthesis, structural characterization and biological activities of metal(II) complexes with Schiff bases derived from 5-bromosalicylaldehyde: Ru(II) complexes transfer hydrogenation

• DOI: 10.1016/j.jscs.2018.06.002
• Publication Date: 2018-06-28T10:25:07Z
• Authors: Kenan Buldurun; Nevin Turan; Ahmet Savcı; Naki Çolak
• Keywords: Transition Metals; Antioxidant Activity; Transition metals; 01 natural sciences; Transfer hydrogenation; Transfer Hydrogenation; 0104 chemical sciences; Carboxylate Ligand; Chemistry; Antiradical Activity; Antioxidant activity; Carboxylate ligand; Antiradical activity; QD1-999

In this study, two novel Schiff base ligands (L1 and L2) derived from condensation of methyl 2-amino-6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate and methyl 2-amino-6-phenyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate, both starting matter with 5-bromo-salicylaldehyde, and their Zn(II) and Ni(II) metal complexes have been prepared using a molar ratio of ligand:metal as 1:1 except the Ru(II) complexes 1:0.5. The structures of the obtained ligands and their metal complexes were characterized by elemental analysis, FT-IR, 1H NMR, 13C NMR, UV–vis, thermal analysis methods, mass spectrometry, and magnetic susceptibility measurements. Antioxidant and antiradical activity of Schiff base ligands and their metal complexes were been evaluated in vitro tests. Antioxidant activities of metal complexes generally were more effectives than free Schiff bases. 1c and 2c were used as catalysts for the transfer hydrogenation (TH) of ketones. 1c, 2c complexes were found to be efficient catalyst for transfer hydrogenation reactions. Keywords: Antioxidant activity, Antiradical activity, Transition metals, Carboxylate ligand, Transfer hydrogenation