MP78-19 SURGICAL MANAGEMENT OF UROTHELIAL CARCINOMA IN PATIENTS WITH UPPER TRACT AND LOWER TRACT UROTHELIAL CARCINOMA: IMPACT OF SURGICAL SEQUENCE

• DOI: 10.1016/j.juro.2017.02.2107
• Publication Date: 2017-04-03T18:35:35Z
• Authors: Tanner Miest; Amir Toussi; R. Jeffery Karnes; Stephen Boorjian; R. Houston Thompson; Matthew Tollefson; Igor Frank; Bradley Leibovich
• Keywords: Upper urinary tract

You have accessJournal of UrologyBladder Cancer: Upper Tract Transitional Cell Carcinoma II1 Apr 2017MP78-19 SURGICAL MANAGEMENT OF UROTHELIAL CARCINOMA IN PATIENTS WITH UPPER TRACT AND LOWER CARCINOMA: IMPACT SEQUENCE Tanner Miest, Amir Toussi, R. Jeffery Karnes, Stephen Boorjian, Houston Thompson, Matthew Tollefson, Igor Frank, and Bradley Leibovich MiestTanner Miest More articles by this author , ToussiAmir Toussi KarnesR. Karnes BoorjianStephen Boorjian ThompsonR. Thompson TollefsonMatthew Tollefson FrankIgor Frank LeibovichBradley View All Author Informationhttps://doi.org/10.1016/j.juro.2017.02.2107AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION OBJECTIVES Urothelial carcinoma can occur in both the upper lower urinary tract; however, natural history disease recurrence outcomes patients who ultimately require radical cystectomy (RC) nephroureterectomy (RNU) is poorly understood. We aim define these populations better inform surveillance strategies following tract resection for urothelial carcinoma. METHODS retrospectively reviewed medical records underwent RC RNU at Mayo Clinic between 1995 2009. Patients had undergone were grouped order. Time resections pathology data time determined, Kaplan-Meier analysis was used evaluate specific overall survival. RESULTS Of 524 our institution, 100 (19%) also RC. 49/100 (49%) initial followed (RC->RNU), 24/100 (24%) (RNU->RC), 27/100 (27%) simultaneous (RC+RNU). The median procedures shorter undergoing RNU->RC (14.6 months) compared RC->RNU (42.6 months). after (RC->RNU) more likely be Grade 3 (80.0%) T3 or T4 (22.7%) than bladder cancer (RNU->RC; 3: 58.3%; T4: 12.5%). Nevertheless, second surgery, there no significant difference survival (DSS, Log-Rank, P=0.28) (OS, P=0.74) groups (DSS: 83.7 months; OS: 110.1 months), 74.3 149.9 RC+RNU 62.5 109.2 CONCLUSIONS Our highlight high frequency synchronous metachronous carcinoma, with nearly 20% requiring Disease occurred rapidly However, presented later higher grade stage presenting RNU. These importance long-term oncologic © 2017FiguresReferencesRelatedDetails Volume 197Issue 4SApril 2017Page: e1039 Advertisement Copyright & Permissions© 2017MetricsAuthor Information Expand PDF downloadLoading ...