Detection of multivessel calcific disease progression in a patient with chronic limb-threatening ischemia using fluorine-18 sodium fluoride positron emission tomography imaging

• DOI: 10.1016/j.jvscit.2023.101137
• Publication Date: 2023-03-04T01:44:00Z
• Authors: Ting-Heng Chou; Molly K. Wynveen; Eleanor T. Rimmerman; Surina Patel; Michael R. Go; Mitchel R. Stacy
• Keywords: Sodium fluoride

Vascular calcification contributes to morbidity and poor clinical outcomes for patients with peripheral artery disease; however, the traditional assessment of calcium burden using computed tomography (CT) imaging or angiography represents already established disease. In present report, we describe a 69-year-old man chronic limb-threatening ischemia who had undergone positron emission tomography/CT fluorine-18 sodium fluoride evaluate relationship between baseline levels tomography-detectable active vascular microcalcification CT-detectable progression 1.5 years later. CT at follow-up identified existing lesions formation new in multiple arteries that demonstrated elevated uptake earlier.