The impact of non-optimum temperatures, heatwaves and cold spells on out-of-hospital cardiac arrest onset in a changing climate in China: a multi-center, time-stratified, case-crossover study

• DOI: 10.1016/j.lanwpc.2023.100778
• Publication Date: 2023-04-29T10:53:07Z
• Authors: Jiangdong Liu; Chuanzhu Lv; Jiaqi Zheng; Chang Pan; Guoqiang Zhang; Huiqiong Tan; Yu Ma; Yimin Zhu; Xiaotong Han; Chaoqian Li; Shengtao Yan; Jingjing Ma; Jianbo Zhang; Chunyi Wang; Yuan Bian; Kai Cheng; Rugang Liu; Yaping Hou; Qiran Chen; Xuan Zhang; Yuguo Chen; Renjie Chen; Feng Xu
• Keywords: Baseline (sea)

Out-of-hospital cardiac arrest (OHCA) is a time-critical and fatal medical emergency that has been linked to non-optimal temperatures. However, the future burden of OHCA due temperatures, heatwaves, cold spells under climate change not well evaluated.We conducted time-stratified case-crossover study in 15 Northern Chinese cities throughout 2020 estimate exposure-response relationships with hourly onset hot seasons. We obtained daily average temperatures by using 20 general circulation models two greenhouse gas emission scenarios: one certain control other relaxed control. Lastly, we projected these scenarios.We analyzed total 29,671 patients found high heatwaves as low were all significantly associated an increased risk onset. Under scenario uncontrolled emissions, attributable fraction (AF) would increase 4.94% 6.99% from 2010s 2090s, respectively. The AF decrease 1.27% 2090s effects be marginal after 2050s. medium scenario, upward trend heat-related become flat, decline cold-related also slow down.Our provides evidence significant morbidity global warming across China. Our findings indicate heat could offset decrements cold, emphasizing importance mitigation policies for limiting reducing risks onset.National Science & Technology Fundamental Resources Investigation Project (2018FY100600, 2018FY100602), National Key R&D Program China (2020YFC1512700, 2020YFC1512705, 2020YFC1512703), Shandong Province (2021ZLGX02, 2021SFGC0503), Natural Foundation (ZR2021MH231), Taishan Pandeng Scholar (tspd20181220), Interdisciplinary Young Researcher Groups University (2020QNQT004), ECCM Clinical Research Center (2021SDUCRCA001, 2021SDUCRCA002), foundation (2020SDUCRCB003), (82272240).