The 2022 outbreak and the pathobiology of the coxsackie virus [hand foot and mouth disease] in India

• DOI: 10.1016/j.meegid.2023.105432
• Publication Date: 2023-04-06T21:19:06Z
• Authors: Nutan A. Chavan; Mallika Lavania; Pooja Shinde; Rima Sahay; Madhuri Joshi; Pragya D. Yadav; Sanjaykumar Tikute; Rishabh Waghchaure; M. Ashok; Anjli Gupta; Mahima Mittal; Vikram Khan; Bashir A. Fomda; Muneer Ahmad; Ved Pratap Tiwari; Pralhad Pote; Ashish Ramchandra...; Aroop Mohanty; Kriti Mohan; Manish Kumar; Anchala Bhardwaj
• Keywords: China; Enterovirus Infections; Humans; COVID-19; India; Child; Hand, Foot and Mouth Disease; Pandemics; 3. Good health; Enterovirus; Disease Outbreaks

Outbreaks of HFMD in children aged <5 years have been reported worldwide and the major causative agents are Coxsackievirus (CV) A16, enterovirus (EV)-A71 and recently CVA6. In India, HFMD is a disease that is not commonly reported. The purpose of the study was to identify the enterovirus type(s) associated with large outbreak of Hand, foot, and mouth disease during COVID-19 pandemic in 2022. Four hundred and twenty five clinical samples from 196-suspected cases were collected from different parts of the country. This finding indicated the emergence of CVA6 in HFMD along with CVA16, soon after the gradual easing of non-pharmaceutical interventions during-pandemic COVID-19 and the relevance of continued surveillance of circulating enterovirus types in the post-COVID pandemic era.