The electro-catalytic activity of nanosphere strontium doped zinc oxide with rGO layers screen-printed carbon electrode for the sensing of chloramphenicol

• DOI: 10.1016/j.microc.2020.105580
• Publication Date: 2020-09-28T18:18:25Z
• Authors: Subash Vetri Selvi; Nandini Nataraj; Shen−Ming Chen
• Keywords: 02 engineering and technology; 0210 nano-technology; 01 natural sciences; 0104 chemical sciences

Abstract Sorting out several toxic threats related to the nominal dosage of drugs, chloramphenicol (CAP) was chosen as a growing emergence of detection. Combined properties of transition metal oxides and rare earth metals were utilized for detection of CAP. Herein, strontium doped zinc oxide with reduced graphene oxide (Sr-ZnO@rGO) was synthesized and employed as an electrochemical sensor on account of good electrical conductivity, large surface area and the electroreduction towards CAP with screen printed carbon electrode (SPCE) as a fabrication electrode. Besides, Sr-ZnO@rGO was synthesized via hydrothermal method that offers good morphologies, surface area, the temperature-controlled process and further implied. In addition, their structural, morphological and elemental composition were investigated with x-ray diffraction spectroscopy (XRD), x-ray photoelectron spectroscopy (XPS), fourier transform infrared spectroscopy (FTIR), field emission scanning electron microscopy (FESEM) analysis. Electrochemical sensing analysis was carried out with cyclic voltammetry and linear sweep voltammetry techniques utilizing (Sr-ZnO@rGO/SPCE). The redox response of chloramphenicol was investigated with the limit of detection 0.131 μ mol L-1 with a linear range of 0.190 to 410.84 μ mol L-1 and 653.06 to 2847.14μ mol L-1 was estimated. The sensitivity was about 1.0554 μA μM-1cm−2. The better performance of Sr-ZnO@rGO/SPCE proved to be an efficient electrochemical sensor for the detection of chloramphenicol with the real sample analysis with milk and powdered milk samples.