Time-to-positivity-based discrimination between Enterobacteriaceae, Pseudomonas aeruginosa and strictly anaerobic Gram-negative bacilli in aerobic and anaerobic blood culture vials

• DOI: 10.1016/j.mimet.2013.02.005
• Publication Date: 2013-02-28T03:55:30Z
• Authors: Gilles Defrance; Gabriel Birgand; Etienne Ruppé; Morgane Billard; Raymond Ruimy; Christine Bonnal; Antoine Andremont; Laurence Armand-L...
• Keywords: Adult; Aged, 80 and over; Male; 0301 basic medicine; Bacteriological Techniques; Gram-Negative Anaerobic Bacteria; Time Factors; Adolescent; Infant; Bacteremia; Middle Aged; 3. Good health; Young Adult; 03 medical and health sciences; Blood; Enterobacteriaceae; Child, Preschool; Pseudomonas aeruginosa; Humans; Female; Child; Gram-Negative Bacterial Infections; Aged

Time-to-positivity (TTP) of first positive blood cultures growing Gram-negative bacilli (GNB) was investigated. When anaerobic vials were positive first, TTP ≤ 18 h differentiated Enterobacteriaceae from strict anaerobic Gram-negative bacilli (PPV 98.8%). When the aerobic ones were first, TTP ≤ 13 h differentiated Enterobacteriaceae from Pseudomonas aeruginosa and other GNB (PPV 80.8%).