First report of human infection caused by Colletotrichum chlorophyti occurring in a post-corneal transplant patient with endophthalmitis

• DOI: 10.1016/j.mmcr.2021.04.002
• Publication Date: 2021-04-21T19:44:06Z
• Authors: Alberto E. Paniz-...; Steven Agemy; Connie Cañete-Gibas; Melissa R. Gitman; Codrin E. Iacob; Inna Necula; Ching-Yi Wang; Lourdes A. Delgad...; Carmita Sanders; Nathan P. Wiederhold; Emilia M. Sordillo; Michael D. Nowak
• Keywords: Keratitis; Emerging; 0301 basic medicine; Medicine (General); Pathogen; QH301-705.5; Case Report; 3. Good health; 03 medical and health sciences; Fungal; R5-920; 0302 clinical medicine; Colletotrichum chlorophyti; Biology (General)

Keratomycosis or mycotic keratitis is recognized as one of the major causes of ophthalmic morbidity worldwide. The most common organisms linked to keratomycosis include Candida spp., Fusarium spp., and Aspergillus spp. However, varieties of saprobic fungi have been reported as causative agents of keratomycosis. Amongst these are members of the genus Colletotrichum. Herein we present the first reported case of C. chlorophyti infection in a post-corneal transplant patient, suggesting an increasing role for Colletotrichum species as emerging human pathogens, particularly in the transplant population.