A comparison study of pathological features and drug efficacy between Drosophila models of C9orf72 ALS/FTD

• DOI: 10.1016/j.mocell.2023.12.003
• Publication Date: 2023-12-22T00:54:47Z
• Authors: Davin Lee; Hae Chan Jeong; Seung Yeol Kim; Jin Yong Chung; Seok Hwan Cho; Kyoung Ah Kim; Jae Ho Cho; Byung Su Ko; In Jun Cha; Chang Geon Chung; Eun Seon Kim; Sung Bae Lee
• Keywords: C9ORF72; Drug Development

Amyotrophic lateral sclerosis is a devastating neurodegenerative disease with complex genetic basis, presenting both in familial and sporadic forms. The hexanucleotide (G