A Liquid to Solid Phase Transition Underlying Pathological Huntingtin Exon1 Aggregation

• DOI: 10.1016/j.molcel.2018.04.007
• Publication Date: 2018-05-10T10:36:44Z
• Authors: Thomas R. Peskett; Frédérique Rau; Jonathan O’Driscoll; Rickie Patani; Alan R. Lowe; Helen R. Saibil
• Keywords: 0301 basic medicine; electron tomography; Saccharomyces cerevisiae; bcs; fluorescence microscopy; Protein Aggregation, Pathological; Article; Phase Transition; Huntingtin exon1; Aggragation; Phase transition; PolyQ; Electron tomography; Fluorescence microscopy; polyQ; 03 medical and health sciences; Humans; Huntingtin exon1; Phase transition; Fluorescence microscopy; Huntingtin Protein; 0303 health sciences; aggregation; Exons; HEK293 Cells; Huntington Disease; Electron tomography; phase transition; huntingtin exon1; PolyQ; Aggragation; Peptides

ISSN:1097-2765<br/>ISSN:1097-4164<br/>Molecular Cell, 70 (4)<br/>