Fatigue and health-related quality of life depend on the disability status and clinical course in RRMS
Quality of life
Multiple Sclerosis
Neurosciences
3. Good health
Multiple sclerosis
Cross-Sectional Studies
Multiple Sclerosis, Relapsing-Remitting
Quality of Life
Disease Progression
Humans
10. No inequality
ta515
Fatigue
Retrospective Studies
DOI:
10.1016/j.msard.2023.104861
Publication Date:
2023-07-05T01:19:27Z
AUTHORS (8)
ABSTRACT
Background: Fatigue is a prominent and disabling symptom of multiple sclerosis (MS), impairing quality life. The disease course relapsing remitting MS (RRMS) individual.ObjectivesWe aimed to study the effects demographic clinical characteristics, as well lifestyle risk factors on experienced fatigue health-related life (HRQoL) among RRMS patients, comparing benign severe types.MethodsAltogether 198 Finnish patients were recruited for this real-life cross-sectional study. Self-reported questionnaires used evaluate by using Scale Motor Cognitive Functions 15D questionnaires. Patients categorized into subgroups based current disability status measured Expanded Disability Status (EDSS) cut-off value 4.5, retrospective divided aggressive RRMS.ResultsAll in all, 73% suffered from fatigue. Lower HRQoL had strong correlation with more (r = -0.719). Higher EDSS was associated lower whole cohort. Older age at onset decreased groups > 4.5. In ≤ 4.5 RRMS, higher number disease-modifying treatments (DMTs) pronounced reduced HRQoL. addition, BMI RRMS. Side (45 %) lack efficacy (26 most common reasons discontinuing DMT. Cessation due side only reason that significantly Use nicotine products, gender, or duration not HRQoL.ConclusionsIndividuals scores are prone experience commonly observed older those DMT switches.
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