High strength and strain alginate fibers by a novel wheel spinning technique for knitting stretchable and biocompatible wound-care materials

• DOI: 10.1016/j.msec.2021.112204
• Publication Date: 2021-05-25T16:21:43Z
• Authors: Zhongda Chen; Jun Song; Yumin Xia; Yuwei Jiang; Luis Larrea Murillo; Olga Tsigkou; Tao Wang; Yi Li
• Keywords: Biocompatible material; Breaking strength; Wound care

Alginate fibrous materials have been applied as wound dressing to enhance healing due its nontoxic, biodegradable, and hemostatic nature. Conventional nonwoven fabrication tactics, however, showed weakness in inflammation, degradation stability mechanical properties. Herein, the wet-spun alginate fibers were prepared by a novel wheel spinning technique, then knitted into dressing. Benefiting from optimized wet parameters agglomeration of multimers, endowed with elevated performances biodegradability, which allowed for feasibility knitting wound-care materials. Using new high strength 173 MPa produced breaking strain up 18% toughness 16.16 MJ*m−3. Meanwhile, reaching 35% tensile 135 37.47 The overall these are significantly higher (up 2 times) than those published literature term toughness. In vitro evaluation revealed that this spun had good aqueous absorbency (50%) sustained biodegradation Furthermore, consequent cell viability study also proved fabric is biocompatible being