Cell membrane camouflaged biomimetic nanoparticles: Focusing on tumor theranostics

• DOI: 10.1016/j.mtbio.2022.100228
• Publication Date: 2022-03-01T17:10:41Z
• Authors: Li Zhu; Yuan Zhong; Shuai Wu; Meng Yan; Yu Cao; Nianlian Mou; Guixue Wang; Da Sun; Wei Wu
• Keywords: Cell membrane; Fluorescence-lifetime imaging microscopy

Nanoparticles (NPs) modified by cell membranes represent an emerging biomimetic platform that can mimic the innate biological functions resulting from various in systems. researchers focus on constructing membrane camouflaged NPs using a wide variety of cells, such as red blood (RBC), macrophages and cancer cells. Cell (CMNPs) inherit composition membranes, including specific receptors, antigens, proteins, for target delivering to tumor, escaping immune clearance, prolonging circulation time, etc. Combining membrane-derived NP cores acted cargo carriers encapsulate imaging agents, CMNPs are widely developed apply tumor techniques, computed tomography (CT), magnetic resonance (MRI), fluorescence (FL) photoacoustic (PA). Herein, this review, we systematically summarize superior imaging, especially highlighting advanced applications different which is provide theoretical supports development precise guided treatment.