Subthalamic and pallidal oscillations and their couplings reflect dystonia severity and improvements by deep brain stimulation

• DOI: 10.1016/j.nbd.2024.106581
• Publication Date: 2024-06-25T23:42:19Z
• Authors: Xinyi Geng; Zhaoyu Quan; Ruili Zhang; Guanyu Zhu; Yingnan Nie; Shouyan Wang; Edmund Rolls; Jianguo Zhang; Li Hu
• Keywords: Subthalamic Nucleus; Local field potential

Deep brain stimulation (DBS) targeting the globus pallidus internus (GPi) and subthalamic nucleus (STN) is employed for treatment of dystonia. Pallidal low-frequency oscillations have been proposed as a pathophysiological marker However, role STN-GPi coupling in relation to dystonia remains unclear.