Vasculitis IgA con nefritis (púrpura de Schönlein-Henoch) tras COVID-19: una serie de casos y revisión de la literatura

• DOI: 10.1016/j.nefro.2021.07.009
• Publication Date: 2021-08-03T02:12:34Z
• Authors: Irene Oñate; Milagros Ortiz; Andrea Suso; Carmen Mon; Karen Galindo; Carolina Lentisco; Rosa Camacho; María Sánchez; Aniana Oliet; Olimpia Ortega; Juan C. Herrero; José A. Cortés; Alejandro Pascual
• Keywords: Schönlein-Henoch purpura; Nephritis; IgA Vasculitis; SARS-CoV-2; Research; Nefropatía; COVID-19; Case Report; Púrpura de Schönlein-Henoch; Apolipoprotein L1; Diseases of the genitourinary system. Urology; Nephropathy; IgA vasculitis; 03 medical and health sciences; 0302 clinical medicine; Vasculitis IgA; Humans; RC870-923; Caso Clínico; Aged

COVID-19 most related glomerular disease to date seems be collapsing glomerulopathy, mostly in young Afroamerican patients with APOL1 gene risk alleles. However, our population, predominant elderly Caucasian patients, biopsied pathology since the beginning of pandemic has been IgA nephritis or Schönlein-Henoch purpura.Since description first case this entity after SARS-CoV-2 infection by research group, three more cases have arisen, which are described following article. In contrast rest vasculitis reported, presented renal function deterioration and all them required immunosupresive therapy. Moreover, some showed incomplete recovery function.This series strengthens hypothesis that may another trigger pathology.