Consequence of stroke for feature recall and binding in visual working memory

• DOI: 10.1016/j.nlm.2021.107387
• Publication Date: 2021-01-18T06:54:56Z
• Authors: Selma Lugtmeijer; Sebastian Schneegans; Nikki A. Lammers; Linda Geerligs; Frank Erik de Leeuw; Edward H.F. de Haan; Paul M. Bays; Roy P.C. Kessels
• Keywords: Cued speech

Visual memory for objects involves the integration, or binding, of individual features into a coherent representation. We used novel approach to assess feature using delayed-reproduction task in combination with computational modeling and lesion analysis. assessed stroke patients neurotypical controls on visual working which spatial arrays colored disks were presented. After brief delay, participants either had report color one disk cued by its location color. Our results demonstrate that, controls, imprecision swap errors (non-target reports) can be explained single source variability. Stroke showed an overall decrease precision both location, only limited evidence deviations from predicted relationship between errors. These primarily deficits reporting items rather than selecting based cue. Atlas-based lesion-symptom mapping that selection deficits, color, associated different profiles. Deficits binding are lesions left somatosensory cortex, bilateral fronto-parietal regions, no anatomical substrates identified location. converge previous reports representations widely distributed brain found across sensory, parietal, temporal, prefrontal cortices. mostly subtle impairments memory, perhaps because areas partly compensate impaired encoding lesioned areas. findings contribute understanding relation memorizing their bound representations.