Psychiatric and neurodevelopmental aspects of Becker muscular dystrophy

• DOI: 10.1016/j.nmd.2019.09.006
• Publication Date: 2019-09-18T18:57:11Z
• Authors: Madoka Mori-Yoshi...; Yukio Mizuno; Sumiko Yoshida; Naoko Ishihara; Narihiro Minami; Emiko Morimoto; Kazushi Maruo; Ikuya Nonaka; Hirofumi Komaki; Ichizo Nishino; Masayuki Sekiguchi; Noriko Sato; Shin'ichi Takeda; Yuji Takahashi
• Keywords: Adult; Male; Adolescent; Developmental Disabilities; Mental Disorders; Brain; Bullying; Middle Aged; 16. Peace & justice; 3. Good health; Muscular Dystrophy, Duchenne; Young Adult; 03 medical and health sciences; 0302 clinical medicine; Risk Factors; Humans; Atrophy; Aged

Little is known about the relationship between Becker Muscular Dystrophy (BMD) and mental disorders. This study aimed to clarify whether BMD a risk factor for psychiatric diseases. We asked genetically or immunohistochemically confirmed patients participate in interview. Participants who consented tests underwent further assessments of intellectual, psychological, neurodevelopmental In total, 76 (73%) 105 (median age, 37 years) completed Of these, 6 had developmental disorders (mental retardation, pervasive disorder), 33/76 (43%) experienced bullying school, 11 exhibited problematic behaviors such as cutting class violent incidents, 16 (schizophrenia spectrum, 5; depressive 4; stress-related disorders, 3; obsessive-compulsive related 2; somatic symptom bipolar 1). Mean IQ was normal, whereas 13/40 (32.5%) participants were state. High trait anxiety found 20/40 (50%) patients, while 15/40 (38.5%) an anxious Review MRI data from 14 revealed brain atrophy caused solely by unrelated any other complication. Our findings suggest that are at developing Physical handicap may influence their state, many them have high anxiety. Parents, teachers, supporters should be mindful daily environment provide support help cope with stress.