Mechanochemical synthesis and characterization of strontium substituted apatite for biomedical application

• DOI: 10.1016/j.oceram.2023.100459
• Publication Date: 2023-09-07T16:38:53Z
• Authors: Yuta Otsuka; Besim Ben-Nissan; Hiroshi Kono; Tetsuo Sasaki; Masafumi Kikuchi
• Keywords: Characterization

Strontium-substituted apatite has been proposed as a promising material for osteoporosis treatment. Several synthesis methods have attempted in the past. In this study, we investigated method known mechanochemical method. Characterization was carried out using different amounts of strontium ions hydroxyapatite (HAp) matrix with FT-IR spectral analysis, X-ray diffraction, lattice constant measurements, differential thermal analysis (DTA), terahertz spectroscopy, and investigation basic morphology scanning electron microscopy (SEM), energy dispersive (EDX). We report that development performance synthetic pathways are more efficient economical than other substituted formation useful biomedical field to produce calcium phosphate-based clinical materials. The FTIR spectra, XRD results revealed mixture dicalcium phosphate dihydrate (DCPD), Ca(OH)2 Sr(OH)2 8H2O phase-transformed into strontium-containing carbonate amorphous by simple