The association between pulmonary tuberculosis recurrence and exposure to fine particulate matter and residential greenness: A population-based retrospective study

• DOI: 10.1016/j.onehlt.2025.101035
• Publication Date: 2025-04-13T01:24:17Z
• Authors: Yuanzhi Di; Ying Peng; Xiaogang Hao; Henan Xin; Tonglei Guo; Jiang Du; Xuefang Cao; Lingyu Shen; Juanjuan Huang; Yijun He; Boxuan Feng; Zihan Li; Jianguo Liang; Chunfu Fang; Ping Zhu; Yu Zhang; Fei Wang; Xiaomeng Wang; Bin Chen; Bingjun Xu; Lei Gao
• Keywords: Association (psychology)

To assess the association of pulmonary tuberculosis (PTB) recurrence with fine particulate matter (PM2.5) and residential greenness using a population-based retrospective study design. All incident PTB patients, registered in Tuberculosis Information Management System (TBIMS) from 2015 to 2019 Quzhou City, China, were included. The data on PM2.5 exposure was extracted China High Air Pollutants dataset level estimated Normalized Difference Vegetation Index (NDVI) values around patient's residence. Cox proportional hazards models used quantify risk recurrence. 6732 Eligible patients included mean age 56.86 years median follow-up time 750 days. Recurrence observed 554 (8.2 %). Exposure NDVI be negatively associated (HR: 0.86, 95 % CI: 0.75-0.98 per 0.1-unit increase). strength between higher greater than that lower concentrations both low high groups (HR:6.62 4.35, p-interaction <0.001). Our findings suggest might increase recurrence, while have protective effect. Like other chronic respiratory diseases, prevention control will also benefit comprehensive environmental management.