Risk factors for nosocomial infections after cardiac surgery in newborns with congenital heart disease

• DOI: 10.1016/j.pedneo.2017.11.014
• Publication Date: 2017-11-23T20:46:24Z
• Authors: Heladia García; Beatriz Cervantes...; Héctor González-C...; Guadalupe Miranda...
• Keywords: Central venous catheter

Congenital heart diseases are among the most common congenital malformations. Approximately 50% of patients with disease undergo cardiac surgery. Nosocomial infections (NIs) main complications and an important cause increased morbidity mortality associated diseases. This study's objective was to identify risk factors development NIs after surgery in newborns disease.This a nested case-control study that included 112 newborns, including 56 cases (with NI) controls (without NI). Variables analyzed perinatal history, malformations, Risk-Adjusted Heart Surgery (RACHS-1) score, perioperative postoperative factors, transfusions, length central venous catheter, nutritional support, mechanical ventilation.Differences were calculated Mann-Whitney-U test, Pearson X2, or Fisher's exact test. A multivariate logistic regression used determine independent factors.Sepsis NI (37.5%), causative microorganisms gram-positive cocci. The non-cardiac malformations (OR 6.1, CI 95% 1.3-29.4), catheter indwelling time > 14 days 3.7, 1.3-11.0), duration ventilation 7 6.6, 2.1-20.1), ≥5 transfusions blood products 3.1, 1.3-8.5). Mortality attributed 17.8%.Newborns >7 at higher for NI. Efforts must focus on preventable infections, especially bloodstream catheter-related which account 20.5% all NIs.