Comparison of image registration methods in patients with non-melanoma skin cancer treated with superficial brachytherapy

• DOI: 10.1016/j.phro.2024.100631
• Publication Date: 2024-08-17T22:52:31Z
• Authors: Marta Szlag; Magdalena Stankie...; Sylwia Kellas-Ślę...; Małgorzata Stąpór...; Agnieszka Cholewka; Agnieszka Pruefer; Piotr Wojcieszek
• Keywords: Medical physics. Medical radiology. Nuclear medicine; 03 medical and health sciences; 0302 clinical medicine; Short Communication; R895-920; Superficial brachytherapy; Skin cancer; Neoplasms. Tumors. Oncology. Including cancer and carcinogens; Deformable image registration; RC254-282

The accumulated dose from sequential treatments of metachronous non-melanoma skin cancer can be assessed using image registration, although guidelines for selecting the appropriate algorithm are lacking. This study shows the impact of rigid (RIR), deformable (DIR) and deformable structure-based (SDIR) algorithms on the skin dose. DIR increased: the maximum dose (39.2 Gy vs 9.4 Gy), the dose to 0.1 cm3 (16.4 Gy vs 7.8 Gy) and the dose to 2 cm3 (7.6 Gy vs 5.7 Gy). RIR only affected the maximum dose, which increased to 17.0 Gy. SDIR correctly translated the dose maps, as none of the parameters changed significantly.