Heat stress aggravates intestinal inflammation through TLR4-NF-κB signaling pathway in Ma chickens infected with Escherichia coli O157:H7

• DOI: 10.1016/j.psj.2021.101030
• Publication Date: 2021-01-28T16:25:53Z
• Authors: Lu-Ping Tang; Wei-Hao Li; Yi-Lei Liu; Jian-Chi Lun; Yong-Ming He
• Keywords: Escherichia coli infection

Heat stress can decrease poultry performance indices, immune function, and intestinal development, which reduce birds' innate protective mechanisms may be more susceptible for pathogens. Ma chickens heat-stressed with 41°C 12 h recovered 7 d had extremely low immunity. In this study, a chicken model induced by heat then infected Escherichia coli O157:H7 was established to explore the of function changes. in + E. (HS coli) group were stressed at d, HS orally administered 1 mL (1 × 10