Effects of dicopper oxide and copper sulfate on growth performance and gut microbiota in broilers

• DOI: 10.1016/j.psj.2021.101224
• Publication Date: 2021-04-27T11:10:32Z
• Authors: A. Forouzandeh; L. Blavi; N. Abdelli; D. Melo-Duran; A. Vidal; M. Rodríguez; A.N.T.R. Monteiro; J.F. Pérez; L. Darwich; D. Solà-Oriol
• Keywords: Clostridium perfringens; Caecum; Litter

An experiment was conducted to determine the effects of two sources copper (Cu) from sulfate (CuSO4) and dicopper oxide (Cu2O, CoRouge) at three levels inclusion (15, 75, 150 mg/kg) on growth performance gut microbiota broilers. A total 840 one-d-old male chickens (Ross 308) were weighed randomly allocated seven dietary treatments: negative control (NC, a basal diet without Cu addition), NC supplemented with 15, or mg Cu/kg CuSO4 Cu2O (12 replicate pens/treatment, 10 chicks per pen). Broilers challenged by reusing an old litter high concentrations in Clostridium perfringens promote necrotic enteritis. Broiler registered d 21, 35, 42. Excreta samples collected 14, 28, 42 for antimicrobial resistance (AMR) analyses. At 43, one broiler pen euthanized obtain ileal content microbial characterization. Body weight 35 daily gain improved (P < 0.05) as dose increased 15 mg/kg mg/kg. Supplementation decreased abundance 0.01) some families such Streptococcaceae Corynebacteriaceae commensal bacteria like Clostridiaceae Peptostreptococcaceae. Phenotypic AMR not different among treatments 14 28. Isolated Enterococcus spp. broilers fed showed higher enrofloxacin, gentamicin, chloramphenicol compared treatments. By contrast, isolated Escherichia coli Cu, either Cu2O, streptomycin NC. This study suggests that supplementing establishes changes regulating bacterial population ileum, which may explain positive impact broilers' performance.