Microbiome-metabolomics analysis insight into the effects of dietary chromium picolinate on abdominal fat deposition and lipid metabolism of ducks

• DOI: 10.1016/j.psj.2025.105040
• Publication Date: 2025-03-15T23:22:19Z
• Authors: Yueqin Xie; Yuxiao Liu; Yang Liu; Bing Wu; Hua Zhao; Guangmang Liu; Gang Tian; Jingyi Cai; Caimei Wu; Jiayong Tang; Gang Jia
• Keywords: Gut microbiome

This research endeavored to explore the impact of Cr-Pic on abdominal fat deposition and lipid metabolism ducks, as well uncover mechanisms at play identify optimal dietary supplementation level Cr-Pic. The results showed that adding 0.6 mg/kg observably increased body weight serum levels adiponectin leptin, decreased total cholesterol, triglyceride, low-density lipoprotein cholesterol in ducks 14 days (P < 0.05). addition % was discovered regulate meat quality through its effects reducing drip loss, downregulating mRNA expression genes involved synthesis liver, upregulating associated with degradation transport these tissues Untargeted metabolic profiling indicated distinct metabolites between Control groups were predominantly pathways involving amino acids. Microbiome analysis administration altered microbial genera related adjustment cecum such increasing proportion Bacteroides Lactobacillus, decreasing proportions Alistipes, Methanobrevibacter, Romboutsia, Peptostreptococcus In summary, shows promise accumulation by regulating intestinal composition acids are linked metabolism.