Sensory neural hearing loss after concurrent cisplatin and radiation therapy for nasopharyngeal carcinoma

• DOI: 10.1016/j.radonc.2004.02.009
• Publication Date: 2004-04-19T07:28:23Z
• Authors: Young-Taek Oh; Chul-Ho Kim; Jin-Hyuk Choi; Seung-Hee Kang; Mison Chun
• Keywords: Adult; Male; Hearing Loss, Sensorineural; Incidence; Carcinoma; Nasopharyngeal Neoplasms; Middle Aged; Combined Modality Therapy; 3. Good health; 03 medical and health sciences; 0302 clinical medicine; Humans; Female; Prospective Studies; Cisplatin; Radiation Injuries

Sensory neural hearing loss (SNHL) was evaluated in the patients who were treated with concurrent chemoradiation therapy for nasopharyngeal carcinoma. Ten from 48 ears showed persistent SNHL. Radiotherapy techniques, radiation dose to inner ear and post-treatment otitis media were significant predicting factors for SNHL.