Lumbar arthrodesis infection by multi-resistant Klebsiella pneumoniae, successfully treated with implant retention and ceftazidime/avibactam

• DOI: 10.1016/j.recote.2018.02.005
• Publication Date: 2018-11-23T13:22:49Z
• Authors: A. Rico-Nieto; F. Moreno-Ramos; N. Fernández-Baillo
• Keywords: Adult; 0301 basic medicine; Lumbar Vertebrae; Arthrodesis; Ceftazidime; Anti-Bacterial Agents; Klebsiella Infections; 3. Good health; Drug Combinations; Klebsiella pneumoniae; 03 medical and health sciences; Drug Resistance, Multiple, Bacterial; Humans; Surgical Wound Infection; Female; Azabicyclo Compounds

There are increasingly more patients with prosthetic implants (orthopaedic prostheses, lumbar instruments, osteosynthesis material). In the last decade, infections caused by carbapenem resistant Enterobacteriaceae have increased (bacteriaemia, abscesses, urinary tract infections...) with great difficulty in treatment and important associated comorbidity. We present the first case of infection of a lumbar instrumentation by Klebsiella pneumoniae producing carbapenemase D, OXA-48 type, and successfully treated.