Generation of a human induced pluripotent stem cell line (SHUPLi002-A) from PBMCs of a healthy female donor

• DOI: 10.1016/j.scr.2024.103422
• Publication Date: 2024-04-15T14:15:54Z
• Authors: Beixu Li; Xing Ye; Junyi Lin; Kaijun Ma; Meng He; Youxin Fang
• Keywords: Germ layer; Lineage (genetic); Pathogenesis

Human induced pluripotent stem cells (iPSCs) have good multi-lineage differentiation potential, which is an ideal model for studying the pathogenesis of diseases and drug screening.Here, we generated iPSC line, SHUPLi002-A, from peripheral blood mononuclear (PBMCs) a healthy 28-year-old female individual using episomal vectors. SHUPLi002-A characterized by expression classical cell markers as well teratoma formation assays to evaluate their capacity in vivo.