Commercial chip-based tunneling magnetoresistance sensor for green-synthesized magnetic nanoparticles assay

• DOI: 10.1016/j.sintl.2024.100288
• Publication Date: 2024-07-29T16:34:06Z
• Authors: Pinaka Elda Swastika; Harlina Ardiyanti; Zurnansyah; Deska Lismawennin...; Nurul Imani Istiq...; Nur Aji Wibowo; Edi Suharyadi
• Keywords: Coprecipitation

Owing to their significant roles in multiple sectors, the demand for high-performance, rapid, user-friendly, and low-cost sensors is crucial biosensing. This paper reports performance of a commercial chip-based tunneling magnetoresistance (TMR) sensor detecting green-synthesized magnetic nanoparticles (MNP) as potential labels. A Simple design consisting TMR chip ALT-025 integrated with an Arduino microcontroller basic differential amplifier was developed provide real-time measurable digital readouts. Three kinds ferrite MNPs (Fe3O4, CoFe2O4 MnFe2O4) synthesized by coprecipitation method on green synthesis approach utilizing Moringa Oleifera extracts. All sample have face-centered cubic inverse spinel structure average grain size 10.3 nm, 9.2 nm 6.1 Fe3O4, MnFe2O4, respectively. Furthermore, soft ferromagnetic behavior identified all magnetization saturation 55.3 emu/g, 37.6 19.3 emu/g The showed promising detection MNPs. For three particles, sensitivity exhibited linear function concentration. related not only particle but also bias field. change output voltage proportional (MBias), indicating that particles higher can produce stronger stray field surface. system successfully detected at different intensities. low limit achieved using these methods. Moreover, remarkable stability repeatability further validated steady signal acquired 30s RSD 0.5-28.5%. Therefore, integration has great advancing various biomolecules.