The versatile applications of polydopamine in regenerative medicine: Progress and challenges

• DOI: 10.1016/j.smaim.2022.11.005
• Publication Date: 2022-12-05T17:42:35Z
• Authors: Shundong Cai; Yuhang Cheng; Chenyue Qiu; Gang Liu; Chengchao Chu
• Keywords: Regenerative Medicine; Biocompatibility

In recent decades, great progress has been made in regenerative medicine with the development of various functional scaffolds, many which have put into practical clinical applications. this process, biomaterials excellent properties played an important role, such as medical metal materials, bioceramics, polymers, etc. Among them, melanin-like polymer polydopamine (PDA) attracts increasing scientific interest and shows good application potential: i) PDA can be used coating material to facilitate loading bioactive molecules; ii) applied main constituent scaffolds optimize performances. review, preparation method polymerization mechanism are first outlined, then advantages PDA, including biocompatibility, strong adhesion, antioxidant property, photothermal properties, introduced. Next, review highlights significant applications medicine, mainly focusing on wound healing, bone repair regeneration, well different forms tissue engineering. Finally, challenges prospects future discussed.