A highly sensitive and selective fluorescence chemosensor for Fe3+ based on rhodamine and its application in vivo imaging

• DOI: 10.1016/j.snb.2017.03.084
• Publication Date: 2017-03-18T17:18:14Z
• Authors: Xiaodong Jin; Shifan Wang; Wenzhu Yin; Tongxiang Xu; Yang Jiang; Qi Liao; Xiaowei Xia; Jingning Liu
• Keywords: 02 engineering and technology; 0210 nano-technology

Abstract We synthesized a rhodamine-based fluorescent probe 1 , which could be used for the optical detection of Fe 3+ . Compared with other commonly coexistent metal ions in aqueous system, it exhibited high sensitivity and selectivity for Fe 3+ , and the detection limit was only 4.2 × 10 −8 M. In addition, the rapid enhancement of fluorescence intensity on addition of Fe 3+ provided a good method for the detection of Fe 3+ . What’s more, the colour change was visible and distinct, so it could be used for the naked-eye detection of Fe 3+ . Furthermore, the fluorescent probe was proved to be effective when used for sensing Fe 3+ in living cells and zebrafish. These results showed its values in biological aspects.