Click synthesis of a quinoline-functionalized hexahomotrioxacalix[3]arene: A turn-on fluorescence chemosensor for Fe3+

• DOI: 10.1016/j.snb.2017.07.048
• Publication Date: 2017-07-10T19:00:21Z
• Authors: Chong Wu; Chuan-Zeng Wang; Qin Zhu; Xi Zeng; Carl Redshaw; Takehiko Yamato
• Keywords: Quinoline; Turn (biochemistry)

Abstract A novel quinoline-functionalized hexahomotrioxacalix[3]arene L was synthesized via Click chemistry and its chemosensing properties with various metal ions were investigated. The chemosensor L exhibited a high selectivity for Fe 3+ with little interference from other environmentally and biologically relevant metal ions, leading to a prominent ‘off-on’ type fluorescent signalling behaviour. Our studies demonstrated that the detection limit on fluorescence response of the sensor to Fe 3+ is in the 10 −7 M range. The mechanism of the interaction between the L and Fe 3+ has been investigated in detail by 1 H NMR spectroscopic titration experiments.