CRISPRi/a screens in human iPSC-cardiomyocytes identify glycolytic activation as a druggable target for doxorubicin-induced cardiotoxicity

• DOI: 10.1016/j.stem.2024.10.007
• Publication Date: 2024-11-07T15:44:04Z
• Authors: Chun Liu; Mengcheng Shen; Yanxia Liu; Amit Manhas; Shane Rui Zhao; Mao Zhang; Nadjet Belbachir; Lu Ren; Joe Z. Zhang; Arianne Caudal; Masataka Nishiga; Dilip Thomas; Angela Zhang; Huaxiao Yang; Yang Zhou; Mohamed Ameen; Nazish Sayed; June-Wha Rhee; Lei S. Qi; Joseph C. Wu
• Keywords: Druggability; Cardiotoxicity