A comprehensive engineering strategy improves potency and manufacturability of a near pan-neutralizing antibody against HIV

• DOI: 10.1016/j.str.2025.04.016
• Publication Date: 2025-05-14T14:37:26Z
• Authors: Mohammad M. Sajadi; Abdolrahim Abbasi; Zahra Rikhtegaran...; Christine Siska; Rutilio Clark; Woo Chi; Michael S. Seaman; Dieter Mielke; Kshitij Wagh; Qingbo Liu; Taylor Jumpa; Randal R. Ketchem; Dung N. Nguyen; William D. Tolbert; Brian G. Pierce; Ben Atkinson; Derrick Deming; Megan Sprague; Andrew Asakawa; David Ferrer; Yasmin Dunn; Sarah Calvillo; Rui Yin; Johnathan D. Guest; Bette Korber; Bryan T. Mayer; Alicia H. Sato; Xin Ouyang; Scott Foulke; Parham Habibzadeh; Maryam Karimi; Arash Aslanabadi; Mahsa Hojabri; Saman Saadat; Roza Zareidoodeji; Mateusz Kędzior; Edwin Pozharski; Alonso Heredia; Hegang Chen; David Montefiori; Guido Ferrari; Marzena Pazgier; George K. Lewis; Joseph G. Jardine; Paolo Lusso; Anthony DeVico